Mimicking the Complexity & Dynamism of the Human Joint
At our company, we are dedicated to developing innovative solutions to address critical healthcare issues, including osteoarthritis, a common degenerative joint disease that affects millions of people worldwide.
To better understand the complex and dynamic microenvironment of the joint and develop potential therapeutic interventions, we have developed a joint model that mimics the biological and physical complexity of joint tissues.
Osteoarthritis models express key biomarkers of disease
Osteoarthritis affects approximately 10% to 15% of adults aged 60 and over worldwide, with its incidence increasing as the population ages. Despite its prevalence, there is no definitive treatment for osteoarthritis.
Our joint model enables us to reproduce the biological and physical complexity of joint tissues and mimic cell-cell and tissue-tissue interactions. By expressing relevant genes and proteins expected in osteoarthritis and modeling vascularization, a potential therapeutic target, we are better placed to understand the mechanisms of the disease and identify potential drug candidates.
Overall, our joint model is a significant step forward in the study of osteoarthritis and potential therapeutic interventions. By mimicking the complex and dynamic microenvironment of the joint and expressing key biomarkers of disease, we can identify potential drug candidates and test their safety and efficacy in a highly controlled setting. With leads identified for disease-modifying drugs in development, we are well-positioned to make a significant breakthrough in finding therapies for this common and growing disabling disease.